Use of vitamin D and infection in patients with chronic kidney disease

Autor: Emanuela Cardoso da Silva, Mônica Taminato, Cassiane Dezoti da Fonseca, Graciana Maria de Moraes, Maria Cristina Barbosa Longo, Cibele Esmanhoto Grothe, Angélica Gonçalves Silva Belasco, Dulce Aparecida Barbosa
Jazyk: English<br />Spanish; Castilian<br />Portuguese
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Zdroj: Revista Brasileira de Enfermagem, Vol 71, Iss suppl 6, Pp 2792-2799
Druh dokumentu: article
ISSN: 1984-0446
0034-7167
DOI: 10.1590/0034-7167-2018-0640
Popis: ABSTRACT Objective: To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment. Method: Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites). Results: A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive. Conclusion: Vitamin D supplementation was a protective factor against infections of all causes.
Databáze: Directory of Open Access Journals
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