Autor: |
Lu Liu, Eric Schepers, Amy Lum, Janet Rice, Nasser Yalpani, Ryan Gerber, Nuria Jiménez-Juárez, Fikru Haile, Alejandra Pascual, Jennifer Barry, Xiuli Qi, Adane Kassa, Matthew J. Heckert, Weiping Xie, Changkui Ding, Jarred Oral, Minh Nguyen, James Le, Lisa Procyk, Scott H. Diehn, Virginia C. Crane, Howard Damude, Carol Pilcher, Russ Booth, Genhai Zhu, Timothy M. Nowatzki, Mark E. Nelson, Albert L. Lu, Gusui Wu |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Toxins, Vol 11, Iss 7, p 383 (2019) |
Druh dokumentu: |
article |
ISSN: |
2072-6651 |
DOI: |
10.3390/toxins11070383 |
Popis: |
Various lepidopteran insects are responsible for major crop losses worldwide. Although crop plant varieties developed to express Bacillus thuringiensis (Bt) proteins are effective at controlling damage from key lepidopteran pests, some insect populations have evolved to be insensitive to certain Bt proteins. Here, we report the discovery of a family of homologous proteins, two of which we have designated IPD083Aa and IPD083Cb, which are from Adiantum spp. Both proteins share no known peptide domains, sequence motifs, or signatures with other proteins. Transgenic soybean or corn plants expressing either IPD083Aa or IPD083Cb, respectively, show protection from feeding damage by several key pests under field conditions. The results from comparative studies with major Bt proteins currently deployed in transgenic crops indicate that the IPD083 proteins function by binding to different target sites. These results indicate that IPD083Aa and IPD083Cb can serve as alternatives to traditional Bt-based insect control traits with potential to counter insect resistance to Bt proteins. |
Databáze: |
Directory of Open Access Journals |
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