Autor: |
Ahmed H. Abd-Ellah, Abdel Aziz E. Tamam, Mostafa Mohammed Khodry |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
|
Zdroj: |
Middle East Fertility Society Journal, Vol 19, Iss 1, Pp 8-12 (2014) |
Druh dokumentu: |
article |
ISSN: |
1110-5690 |
DOI: |
10.1016/j.mefs.2013.09.002 |
Popis: |
Objective: The aim of the current study was to compare blood loss in pre- and post-operatively rectally administered 600 μg of misoprostol in elective cesarean delivery, in order to determine the optimal time for drug administration (CS). Study design: A 30-month prospective, single-blind, randomized, clinical trial was done in the Qena University Hospital, Egypt, from January 2010 to October, 2012. Methods: Intervention consisted of pre and post-operative rectally administered misoprostol. At baseline, there were no significant differences in the demographic and obstetric variable between groups. Primary outcome measures were differences in intra-operative and postoperative blood loss between groups. Secondary outcomes measures were hemoglobin levels pre and operative (24 h after CS) and the need for additional uterotonic drugs. Results: A total of 300 subjects were enrolled (pre-operative administrated rectally misoprostol n = 150, post-operative administrated rectally misoprostol n = 150). Subjects receiving pre-operative misoprostol achieved significantly lower blood loss compared to those receiving post-operative misoprostol (620 ± 291 ml vs. 898 ± 321 ml, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|