A physiological model of patient-reported breathlessness during daily activities in COPD

Autor:	C. J. Jolley, J. Moxham
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Activities chronic obstructive pulmonary disease daily living dyspnoea pathophysiology respiratory mechanics Diseases of the respiratory system RC705-779
Zdroj:	European Respiratory Review, Vol 18, Iss 112, Pp 66-79 (2009)
Druh dokumentu:	article
ISSN:	0905-9180 1600-0617
Popis:	Breathlessness during daily activities has a significant impact on quality of life in chronic obstructive pulmonary disease. Herein, we present a physiological model of patient-reported breathlessness based on the relationship between ventilatory load, respiratory muscle capacity, neural respiratory drive and neuromechanical dissociation during daily activities. This model should facilitate an understanding of the mechanisms driving increased intensity of breathlessness during daily activities and the relief of breathlessness following medical or surgical interventions. The model should also provide a structure on which to base the development of patient-reported outcome instruments to measure the severity of breathlessness during daily activities in chronic obstructive pulmonary disease.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ddfa54f0dd4f400b977a781fe3815503 Zobrazit plný text záznamu View record in DOAJ