Level of proinflammatory cytokines in children with various clinical forms of functional dyspepsia
| Autor: | Natalia Shevchenko, Kostiantyn Voloshyn, Tetiana Zimnytska, Liudmyla Rakovska, Tetiana Holovko, Nataliya Panko |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of V. N. Karazin Kharkiv National University: Series Medicine, Iss 38, Pp 56-62 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2313-6693 2313-2396 |
| DOI: | 10.26565/2313-6693-2019-38-07 |
| Popis: | Objective was to study the level of tumor necrosis factor α (TNF-α) and interleukin 1α (IL-1α) in the blood of children with various forms of functional dyspepsia in accordance with various endoscopic changes of the gastric mucosa. Materials and methods. 79 school age children with functional dyspepsia were examined. The diagnosis was made in accordance with the recommendations of the Rome Criteria IV (2016). All patients underwent endoscopic examination of the esophagus, stomach and duodenum to exclude destructive changes of the mucous membrane. The level of TNF-α and IL-1α in the blood serum was determined by enzyme immunoassay. Statistical processing of the results obtained was performed using Microsoft Excel 2010. Results. The average level of TNF-α in the total group was 463.22±27.4 pg/ml, which statistically significantly exceeded this indicator in the control group (26.76±1.10 pg/ml; p |
| Databáze: | Directory of Open Access Journals |
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