Androgens show sex-dependent differences in myelination in immune and non-immune murine models of CNS demyelination

Autor: Amina Zahaf, Abdelmoumen Kassoussi, Tom Hutteau-Hamel, Amine Mellouk, Corentine Marie, Lida Zoupi, Foteini Tsouki, Claudia Mattern, Pierre Bobé, Michael Schumacher, Anna Williams, Carlos Parras, Elisabeth Traiffort
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36846-w
Popis: Androgen effects have been poorly studied in demyelinating diseases in females. Here, authors show androgen requirement for proper myelin regeneration in females and the critical need to consider male-female differences in multiple sclerosis patients.
Databáze: Directory of Open Access Journals