Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine
| Autor: | Lin-Lei Chen, Gilbert T. Chua, Lu Lu, Brian Pui-Chun Chan, Joshua Sung-Chih Wong, Calvin Chit-Kwong Chow, Tak-Ching Yu, Agnes Sze-Yin Leung, Shu-Yan Lam, Tak-Wai Wong, Hing-Wai Tsang, Ian Chi-Kei Wong, Kwok-Hung Chan, Kwok-Yung Yuen, Patrick Ip, Mike Yat-Wah Kwan, Kelvin Kai-Wang To |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Emerging Microbes and Infections, Vol 11, Iss 1, Pp 543-547 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2222-1751 22221751 |
| DOI: | 10.1080/22221751.2022.2035195 |
| Popis: | The novel SARS-CoV-2 Omicron variant may increase the risk of re-infection and vaccine breakthrough infections as it possesses key mutations in the spike protein that affect neutralizing antibody response. Most studies on neutralization susceptibility were conducted using specimens from adult COVID-19 patients or vaccine recipients. However, since the paediatric population has an antibody response to SARS-CoV-2 infection that is distinct from the adult population, it is critical to assess the neutralization susceptibility of pediatric serum specimens. This study compared the neutralization susceptibility of serum specimens collected from 49 individuals of |
| Databáze: | Directory of Open Access Journals |
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