| Autor: |
Engi Ahmed, Mathieu Fieldès, Chloé Bourguignon, Joffrey Mianné, Aurélie Petit, Nasri Amel, Florent Foisset, Carine Bourdais, Isabelle Vachier, Said Assou, John De Vos, Arnaud Bourdin |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 77, Iss , Pp 103437- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2024.103437 |
| Popis: |
Human pluripotent stem cells (hiPSC) represent a unique opportunity to model lung development and chronic bronchial diseases. We generated a hiPSC line from a highly characterized healthy heavy smoker male donor free from emphysema or tobacco related disease. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using integration-free Sendai virus. The cell line had normal karyotype, expressed pluripotency hallmarks, and differentiated into the three primary germ layers.The reported UHOMi007-A iPSC line may be used as a control to model lung development, study human chronic bronchial diseases and drug testing. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
