The association of vitamin B12 deficiency and metformin

Autor:	Pilar Cean, Claudia Folino, Vanina Pagotto, Julio César Bragagnolo, Analía Esther Dagum, Alejandro Daín, Javier Farias, Gustavo Frechtel, Claudio González, Susana Salzberg, Cristian Suárez Cordo, Jorge Alvariñas
Jazyk:	Spanish; Castilian
Rok vydání:	2022
Předmět:	vitamina b12 metformina diabetes mellitus tipo 2. Nutritional diseases. Deficiency diseases RC620-627 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Revista de la Sociedad Argentina de Diabetes, Vol 56, Iss 2Sup, Pp 2-8 (2022)
Druh dokumentu:	article
ISSN:	0325-5247 2346-9420
DOI:	10.47196/diab.v56i2Sup.529
Popis:	Metformin is the most widely used oral antidiabetic agent for the treatment of type 2 diabetes (T2D) and the association of the use of this drug with vitamin B12 deficiency has been described. A review of studies was carried out to find out the evidence of this association and the recommendations for its detection, prevention and treatment. The reported prevalence of vitamin B12 deficiency in patients treated with metformin ranged from 5.8% to 52% in the different series. Older patients, those who received metformin at high doses and for a longer time, and those who do not consume food of animal origin, are those who are at greater risk of suffering from this deficit.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fa274942a34b45df8e692891fdbff869 Zobrazit plný text záznamu View record in DOAJ