| Autor: |
Paulo Goberlânio de Barros Silva, Tayane Oliveira Gonçalves, Ana Mirian da Silva Cavalcante, Erick Ibraim Carlos da Costa, João Vitor de Paula Freitas, Osias Vieira de Oliveira Filho, Thinali Sousa Dantas |
| Jazyk: |
English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Revista Brasileira de Cancerologia, Vol 70, Iss 3 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2176-9745 |
| DOI: |
10.32635/2176-9745.RBC.2024v70n3.4696 |
| Popis: |
Introduction: Oral squamous cell carcinoma (OSCC) presents a high tendency of lymph node metastasis (LNM). Objective: Determine which risk factors play a significant role in metastasis to cervical lymph nodes and to evaluate the influence of nodal involvement on overall survival of patients with OSCC. Method: Medical records of 350 patients with OSCC were retrospectively reviewed. The data were analyzed using the chi-square, Fisher’s exact and log-rank Mantel Cox tests and multinomial and Cox logistic regression. Results: Of the 350 medical records evaluated, 251 reported N0, 75 N1, 16 N2 and 8 N3. Male gender, referrals from private health care providers, T3/4 stage and non-surgical treatments were associated with LNM. In multivariate analysis, men and T3/4 tumors were shown to be independent risk factors for LNM. The independent risk factors for survival were male gender, nodal involvement (p = 0.017) and non-surgical treatment. Conclusion: Male gender and T-stage are risk factors for LNM in patients with OSCC. Moreover, the presence of LNM and age >65 years are associated with poor overall survival.urvivor. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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