Role of tubular cell-derived exosomes in renal ischemia reperfusion injury

Autor: Jin-zhu Huang, Yan-zi Zhang, Cui-yu Yang, Ai-sha Zhang, Xiao-lu Sui, Yun-peng Xu, Ting-fei Xie, Ji-hong Chen
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Linchuang shenzangbing zazhi, Vol 24, Iss 11, Pp 946-950 (2024)
Druh dokumentu: article
ISSN: 1671-2390
DOI: 10.3969/j.issn.1671-2390.2024.11.009
Popis: Renal ischemia reperfusion injury refers to a pathophysiological phenomenon that aggravates the degree of renal injury due to the restoration of blood supply after transient ischemia of renal tissue. It has been found that renal tubular cell-derived exosomes alleviate renal ischemia reperfusion injury through anti-inflammatory, antioxidant, inhibition of apoptosis, promotion of tissue regeneration and activation of autophagy . This review will discuss the protective effect of tubular cell-derived exosomes on renal ischemia reperfusion injury, in order to provide a theoretical basis for the clinical diagnosis, treatment and early prevention of renal ischemia reperfusion injury.
Databáze: Directory of Open Access Journals