Inflammation, Left Ventricular Mass Index and Chronic Renal Failure in Diabetic Patients

Autor: Egemen Cebeci, Nilay Şengül Samancı, Sami Uzun, Serhat Karadağ, Meltem Gürsu, Tuba Elif Şenel Özler, Mustafa Velet, Savaş Öztürk
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Haseki Tıp Bülteni, Vol 58, Iss 2, Pp 129-134 (2020)
Druh dokumentu: article
ISSN: 1302-0072
2147-2688
DOI: 10.4274/haseki.galenos.2020.5662
Popis: Aim:The aim of this study was to determine the relationship between left ventricular hypertrophy (LVH) and inflammatory markers in patients with type 2 Diabetes Mellitus (T2DM) with diabetic nephropathy at different stages.Methods:Our study was a cross-sectional study involving patients with various stage of T2DM. Patients with LVH were identified by 2D echocardiography. Plasma human tumor necrosis factor alpha (TNF-α), interleukin (IL)-1, IL-6, vaspin, vispatin and midkine were measured.Results:A total of 59 T2DM patients (56% women) with a mean age of 56.1±8.8 years were included in the study. The mean left ventricular mass index was 129±30. LVH was detected in 62.7% of the patients. Patients with an estimated glomerular filtration rate (eGFR) of
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