SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in Mice

Autor:	Mariana Baz, Nikita Deshpande, Charlie Mackenzie-Kludas, Francesca Mordant, Danielle Anderson, Kanta Subbarao
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	COVID-19 coronavirus disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses respiratory infections Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 28, Iss 11, Pp 2352-2355 (2022)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2811.220718
Popis:	We assessed cross-reactivity to BA.1, BA.2, and BA.5 of neutralizing antibodies elicited by ancestral, Delta, and Omicron BA.1 SARS-CoV-2 infection in mice. Primary infection elicited homologous antibodies with poor cross-reactivity to Omicron strains. This pattern remained after BA.1 challenge, although ancestral- and Delta-infected mice were protected from BA.1 infection.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fa1e7f5914a84bffb6b090f925d9d72a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF