Effects of different acupuncture manipulations on protein expression in the parietal cortex of spontaneously hypertensive rats

Autor: Jiaojuan Wu, Tianxiao Zeng, Jingrong Liang, Xudong Zhang, Qi Xie, Taotao Lv, Pui Yee Wong, Zhi Ji, Qingguo Liu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Traditional Chinese Medical Sciences, Vol 8, Iss 3, Pp 257-264 (2021)
Druh dokumentu: article
ISSN: 2095-7548
DOI: 10.1016/j.jtcms.2021.07.009
Popis: Objective: To analyze the effects of twirling reinforcing and reducing manipulations on protein expression in parietal cortex of spontaneously hypertensive rats (SHRs), and elucidate the main mechanisms and differences between two manipulations in hypertension treatment. Methods: Rats were randomly divided into the control, model, twirling reinforcing manipulation (TRFM), and twirling reducing manipulation (TRDM) groups. The control and model groups received catch and fixation stimulations once a day for 14 days. The TRFM and TRDM groups were intervened once a day for 20 min for 14 days. On days 0, 2, 6, 10, and 14 after acupuncture, rat systolic blood pressures (SBPs) were measured. Differential protein (DP) expression in the rat parietal cortices was detected. Thereafter, GO functional significance and KEGG pathway enrichment analyses were performed. Results: Compared with the model group, SBP of rats in the TRDM and TRFM groups decreased on days 6 and 10 of acupuncture, respectively (P = .009; P
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