| Autor: |
Claudia Boettcher, Boris Utsch, Angela Galler, Corinna Grasemann, Martin Borkenstein, Christian Denzer, Bettina Heidtmann, Sascha R. Tittel, Reinhard W. Holl, DPV initiative |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Frontiers in Endocrinology, Vol 11 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1664-2392 |
| DOI: |
10.3389/fendo.2020.00052 |
| Popis: |
Background: To apply and evaluate various equations for estimated glomerular filtration rates (eGFR) in a large paediatric type 1 diabetes population and compare the eGFR values with urinary creatinine clearances (UCC) in a subset of patients.Methods: Six eGFR formulae applicable for children and adolescents were used for calculation of eGFR values in 36,782 children/adolescents with type 1 diabetes. Via regression models, factors influencing eGFR values were identified. eGFR values were compared with measured UCC in 549 patients. Spearman correlation coefficients were given to assess the relation of eGFR and UCC values. Bland-Altman-Plots with corresponding linear regression were drawn to evaluate the agreement between eGFR and UCC.Results: eGFR values differed widely depending on the formula used, resulting in a percentage of pathological values |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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