Early onset metastatic colorectal cancer in Australia

Autor: A. Jalali, S. Smith, G. Kim, H. Wong, M. Lee, J. Yeung, M. Loft, R. Wong, J.D. Shapiro, S. Kosmider, J. Tie, S. Ananda, B. Ma, M. Burge, R. Jennens, B. Lee, J. Johns, L. Lim, A. Dean, L. Nott, P. Gibbs
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cancer Treatment and Research Communications, Vol 40, Iss , Pp 100827- (2024)
Druh dokumentu: article
ISSN: 2468-2942
DOI: 10.1016/j.ctarc.2024.100827
Popis: Background: Colorectal cancer (CRC) incidence and mortality rates have been increasing among young patients (YP), for uncertain reasons. It is unclear whether YP have a distinct tumor biology or merit a different treatment approach to older patients (OP). Methods: We reviewed prospectively collected data from consecutive patients with metastatic CRC (MCRC) enrolled in the multi-site Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) Australian registry. Clinicopathological features, treatment and survival outcomes were compared between YP (
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