Five Antiretroviral Drug Class–Resistant HIV-1 in a Treatment-Naïve Patient Successfully Suppressed with Optimized Antiretroviral Drug Selection
| Autor: | Joseph M. Volpe PhD, Douglas J. Ward MD, Laura Napolitano MD, Pham Phung BS, Jonathan Toma BS, Owen Solberg PhD, Christos J. Petropoulos PhD, Charles M. Walworth MD |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Journal of the International Association of Providers of AIDS Care, Vol 14 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2325-9574 2325-9582 23259574 |
| DOI: | 10.1177/2325957415596229 |
| Popis: | Transmitted HIV-1 exhibiting reduced susceptibility to protease and reverse transcriptase inhibitors is well documented but limited for integrase inhibitors and enfuvirtide. We describe here a case of transmitted 5 drug class–resistance in an antiretroviral (ARV)-naïve patient who was successfully treated based on the optimized selection of an active ARV drug regimen. The value of baseline resistance testing to determine an optimal ARV treatment regimen is highlighted in this case report. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|