The Association Between Reorganization of Bilateral M1 Topography and Function in Response to Early Intensive Hand Focused Upper Limb Rehabilitation Following Stroke Is Dependent on Ipsilesional Corticospinal Tract Integrity

Autor: Mathew Yarossi, Jigna Patel, Qinyin Qiu, Supriya Massood, Gerard Fluet, Alma Merians, Sergei Adamovich, Eugene Tunik
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Frontiers in Neurology, Vol 10 (2019)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2019.00258
Popis: Transcranial magnetic stimulation (TMS) induced motor evoked potentials (MEPs) are an established proxy of corticospinal excitability. As a binary measure, the presence (MEP+) or absence (MEP-) of ipsilesional hemisphere MEPs early following stroke is a robust indicator of long-term recovery, however this measure does not provide information about spatial cortical reorganization. MEPs have been systematically acquired over the sensorimotor cortex to “map” motor topography. In this investigation we compared the degree to which functional improvements resulting from early (
Databáze: Directory of Open Access Journals