| Autor: |
Oliveira Joao Batista A, Baruffi Ricardo LR, Petersen Claudia G, Mauri Ana L, Nascimento Adriana M, Vagnini Laura, Ricci Juliana, Cavagna Mario, Franco Jose G |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Reproductive Biology and Endocrinology, Vol 10, Iss 1, p 94 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1477-7827 |
| DOI: |
10.1186/1477-7827-10-94 |
| Popis: |
Abstract Background The objective was to present a new ovarian response prediction index (ORPI), which was based on anti-Müllerian hormone (AMH) levels, antral follicle count (AFC) and age, and to verify whether it could be a reliable predictor of the ovarian stimulation response. Methods A total of 101 patients enrolled in the ICSI programme were included. The ORPI values were calculated by multiplying the AMH level (ng/ml) by the number of antral follicles (2–9 mm), and the result was divided by the age (years) of the patient (ORPI=(AMH x AFC)/Patient age). Results The regression analysis demonstrated significant (PP=0.006) and collecting greater than or equal to 4 oocytes (OR: 49.25; PPP Conclusions The ORPI exhibited an excellent ability to predict a low ovarian response and a good ability to predict a collection of greater than or equal to 4 MII oocytes, an excessive ovarian response and the occurrence of pregnancy in infertile women. The ORPI might be used to improve the cost-benefit ratio of ovarian stimulation regimens by guiding the selection of medications and by modulating the doses and regimens according to the actual needs of the patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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