| Autor: |
G. Schmalz, I. Davarpanah, J. Jäger, R.F. Mausberg, B. Krohn-Grimberghe, J. Schmidt, R. Haak, U. Sack, Dirk Ziebolz |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Microbiology, Immunology and Infection, Vol 52, Iss 3, Pp 386-394 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1684-1182 |
| DOI: |
10.1016/j.jmii.2017.07.016 |
| Popis: |
Background: Aim of this cross-sectional study was the investigation of associations between different rheumatoid arthritis (RA)-related blood parameters and periodontal condition as well as selected periodontal pathogenic bacteria in RA patients under methotrexate (MTX) immunosuppression. Methods: Periodontal probing depth (PPD), bleeding on probing (BOP) and clinical attachment loss (CAL) were assessed. Periodontal condition was classified into: no/mild and moderate or severe periodontitis (P). Prevalence of selected periodontal pathogenic bacteria and concentration of matrix metalloproteinase 8 (MMP-8) was assessed from the gingival crevicular fluid (GCF) using PCR and ELISA, respectively. Blood samples were analyzed for the concentration of selected rheumatoid parameters. Statistical analysis: t-test, Mann–Whitney-U-Test, exact Fisher tests or chi square test (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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