The effect of donor–recipient sex matches on lung transplant survival: An analysis of the United Network for Organ Sharing databaseCentral MessagePerspective

Autor: Elizabeth Profozich, BS, Abul Kashem, MD, PhD, Roh Yanagida, MD, PhD, Manish Suryapalam, BS, Ke Cheng, PhD, Hiromu Kehara, MD, PhD, Norihisa Shigemura, MD, PhD, Yoshiya Toyoda, MD, PhD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JTCVS Open, Vol 18, Iss , Pp 400-406 (2024)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2024.01.018
Popis: Objective: To investigate the impact of donor–recipient (DR) sex matches on survival after lung transplantation while controlling for size difference in the United Network of Organ Sharing (UNOS) database. Methods: We performed a retrospective study of 27,423 lung transplant recipients who were reported in the UNOS database (January 2005-March 2020). Patients were divided into groups based on their respective DR sex match: male to male (MM), male to female (MF), female to female, (FF), and female to male (FM). Kaplan–Meier curve and Cox regression with log-rank tests were used to assess 1-, 3-, 5-, and 10-year survival. We also modeled survival for each group after controlling for size-related variables via the Cox regression. Results: Kaplan–Meier curves showed overall significance at 1-, 3-, 5-, and 10-year end points (P
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