The Potential of Indole Alkaloids in Bone Health and Osteoporosis Management

Autor: Anna Caruso, Virginia Caira, Hussein El-Kashef, Carmela Saturnino
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Applied Sciences, Vol 14, Iss 18, p 8124 (2024)
Druh dokumentu: article
ISSN: 2076-3417
DOI: 10.3390/app14188124
Popis: Indole alkaloids, a class of plant-derived nitrogen-containing compounds, have emerged as promising candidates for osteoporosis treatment. Their favorable biocompatibility profile demonstrated efficacy in preclinical models, and low reported toxicity make them attractive alternatives to existing therapies. This review focuses on the therapeutic potential of specific indole alkaloids, including vindoline, rutaecarpine, harmine, and its derivatives, in promoting bone health and managing osteoporosis.
Databáze: Directory of Open Access Journals