Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

Autor: Malgorzata E. Quinn, Qingnian Goh, Mitsutoshi Kurosaka, Dilani G. Gamage, Michael J. Petrany, Vikram Prasad, Douglas P. Millay
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15665
Popis: Cellular fusion is fundamental for skeletal muscle development. Here the authors show that myomerger is expressed in myoblasts, is essential for myoblast fusion in mice, and in co-operation with myomaker confers fusogenic ability to non-fusogenic cells.
Databáze: Directory of Open Access Journals