A Ratiometric and Colorimetric Hemicyanine Fluorescent Probe for Detection of SO2 Derivatives and Its Applications in Bioimaging

Autor: Yan-Hong Qin, Xiao-Yi Jiang, Yuan-Fang Que, Jing-Yi Gu, Tong Wu, Ayinazhaer Aihemaiti, Ke-Xin Shi, Wen-Yu Kang, Bi-Ying Hu, Jin-Shuai Lan, Yue Ding, Tong Zhang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Molecules, Vol 24, Iss 21, p 4011 (2019)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules24214011
Popis: Based upon the intramolecular charge transfer (ICT) mechanism, a novel ratiometric fluorescent probe EB was developed to detect SO32−/HSO3−. The probe displayed both colorimetric and ratiometric responses toward SO32−/HSO3−. It displayed a quick response (within 60 s), good selectivity and high sensitivity (a detection limit of 28 nM) towards SO32−/HSO3−. The SO32−/HSO3− sensing mechanism was confirmed as the Michael addition reaction by ESI-MS. Moreover, the probe could be applied to measure the level of sulfite in real samples, like sugar and chrysanthemum, and it could also be used to detect SO32−/HSO3− in HepG2 cells through confocal fluorescence microscopy, which proved its practical application in clinical diagnosis.
Databáze: Directory of Open Access Journals
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