Effect of intravenous Vitamin C on sleep quality in hemodialysis patients

Autor: Espahbodi F (MD), Emami Zeydi A (MSc), Gholipour Baradari A (MD), Khademloo M (PhD)
Jazyk: perština
Rok vydání: 2011
Předmět:
Zdroj: مجله دانشگاه علوم پزشکی گرگان, Vol 13, Iss 2, Pp 44-52 (2011)
Druh dokumentu: article
ISSN: 1562-4765
2008-4080
Popis: Background and Objective: Poor sleep quality is common among hemodialysis patients and can potentially predict morbidity, mortality and quality of life in these patients. On the other hand, hemodialysis patients are encountered with vitamin C deficiency. The purpose of this study was to determine the effect of intravenous vitamin C on sleep quality in hemodialysis patients. Materials and Methods: In this double blind randomized clinical trial, 60 qualified hemodialysis patients were gone under investigation in Sari a city located in North of Iran during 2010. Patients randomly allocated in two equal intervention and control groups. The main measured outcome was the Pittsburg sleep quality index (PSQI) which consists of seven components. At the end of each hemodialysis session, Intervention group received vitamin C vial (500mg/5cc) intravenously, three times a week for 8 weeks and control group received normal saline in a same way. Data were collected at pretreatment and after two months of treatment. Data were analyzed by Independent t test, Paired t test, Wilcoxon and Chi-Square tests. Results: The result indicated that the sleep quality improves significantly in vitamin C group but not in control group (P
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