Molecular Organization of the Skin Barrier

Autor:	Lars Norlén
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Cryo-electron microscopy molecular organization permeability barrier Dermatology RL1-803
Zdroj:	Acta Dermato-Venereologica, Vol 103 (2023)
Druh dokumentu:	article
ISSN:	0001-5555 1651-2057
DOI:	10.2340/actadv.v103.13356
Popis:	Cryo-electron microscopy of vitreous sections allows for investigation directly in situ of the molecular architecture of skin. Recently, this technique has contributed to the elucidation of the molecular organization of the skin’s permeability barrier and its stepwise formation process. The aim of this review is to provide an overview of the procedure for cryo-electron microscopy of vitreous sections, its analysis using atomic detail molecular dynamics modelling and electron microscopy simulation, and its application in the investigation of the barrier structure and formation process of the skin.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f910a93e496840a2a8d0be656d838406 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF