Effect of iron therapy on red cell indices and hemoglobin subtypes on patients with beta-thalassemia trait who developed iron-deficiency anemia: a tertiary center experience

Autor: Sawsan M Moeen, Ahmad F Thabet, Marwa M Thabet
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: The Egyptian Journal of Internal Medicine, Vol 31, Iss 4, Pp 741-745 (2019)
Druh dokumentu: article
ISSN: 1110-7782
2090-9098
DOI: 10.4103/ejim.ejim_38_19
Popis: Background The combination of beta-thalassemia trait (BTT) and iron-deficiency anemia (IDA) is an interesting common issue in our country. However, treatment of this condition is challenging. Objectives This prospective observational study was designed to evaluate the effect of oral iron therapy on red cell indices, iron status, and hemoglobin A2 levels in patients with BTT who developed IDA. Patients and methods A total of 50 patients with BTT who developed IDA were included. A complete blood count, iron status, and follow-up hemoglobin electrophoresis by high-performance liquid chromatography were done. The patients with BTT received oral iron therapy of 60 mg elemental iron three times/day for a period of 5 months, and the investigations were repeated after 3 and 5 months of treatment. Results There was a statistically significant increase in hemoglobin level (P
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