| Autor: |
Ana Carolina Contente Braga de Souza, Maria Clara Neres Iunes de Oliveira, Gabriela Nascimento de Lemos, Emanuele Rocha da Silva, Ícaro José Araújo de Souza, Wanderson Maia da Silva, Angélica Leite de Alcântara, Nivin Mazen Said, Lorena Vilhena de Moraes, João Felício Abrahão Neto, Simone Rodrigues dos Passos, Ádria Aline Alves Monteiro, Natércia Neves Marques de Queiroz, Franciane Trindade Cunha de Melo, Karem Miléo Felício, Lilian de Souza D’Albuquerque Silva, Daniela Lopes Gomes, Neyla Arroyo Lara Mourão, Pedro Paulo Freire Piani, Isabel Jane Campos Lobato, João Soares Felício |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-8 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1758-5996 |
| DOI: |
10.1186/s13098-022-00817-w |
| Popis: |
Abstract Background Type 1 Diabetes Mellitus (T1DM) impacts health-related quality of life (HRQoL). Cross-sectional studies suggest that low levels of vitamin D (VD) may impair HRQoL, however, the effect of VD supplementation on quality of life in T1DM patients has not yet been clarified. Our study evaluated the effects of high-dose VD supplementation on HRQoL in T1DM. Methods We performed a prospective study with 64 patients receiving cholecalciferol (4000 IU/day for patients with 25-OH-vitamin D [25(OH)D] between 30 and 60 ng/mL, and 10,000 IU/day for those with 25(OH)D below 30 ng/mL) for 12 weeks, as part of a research protocol. HRQoL was assessed with EuroQol instruments (EQ-5D and EQ-VAS). Results There was an improvement in global EQ-5D index, and analysing specifically the EQ-5D domains, we observed an improvement in mobility (1.3 ± 0.6 versus 1.1 ± 0.3, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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