Autor: |
Hamish T. J. Gilbert, Venkatesh Mallikarjun, Oana Dobre, Mark R. Jackson, Robert Pedley, Andrew P. Gilmore, Stephen M. Richardson, Joe Swift |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-019-11923-1 |
Popis: |
Cells must be robust to the mechanical demands of their environments. Here, Gilbert et al. expose cells to high-intensity strain cycling and use proteomics to identify a protein, SUN2, that behaves as a strain-induced breakpoint that can decouple the nucleoskeleton from the cytoskeleton. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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