Estimation of BMP-15 gene expression and its Association to Hormonal Profile in Iraq Patient with Polycystic Ovary Syndrome
| Autor: | Zainab Ameen Khadhum, Mahdi Saber Al-deresawi |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Wasit Journal for Pure Sciences, Vol 3, Iss 2 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2790-5233 2790-5241 |
| DOI: | 10.31185/wjps.401 |
| Popis: | Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting reproductive aged women. The objective of this study was determine the gene expression levels in patients with PCOS and its reflects in hormonal reproductive : Luteinizing hormone(LH), Prolactin hormone(PRL) , Testosterone hormone (T), Follicle Stimulating hormone (FHS) , estradiol (E2). Fifty patient with PCOS and twenty healthy control group recruited from the Al-Zahra Teaching Hospital and AL-karama Teaching Hospital, in Wasit provinces/Iraq ,based on criteria of Rotterdam.The hormonal profile was carried out by Addendum-Mini VIDAS apparatus. BMP-15 gene expression was estimated by quantitative real-time polymerase chain reaction (qRT-PCR). The mean of Testosterone(1.58±0.17), prolactin (18.42± 1.12), Luteinizing hormone (10.98 ± 0.89 ) was a significant (P |
| Databáze: | Directory of Open Access Journals |
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