Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages

Autor: Wei-Chiao Huang, Moustafa T. Mabrouk, Luwen Zhou, Minami Baba, Mayumi Tachibana, Motomi Torii, Eizo Takashima, Emily Locke, Jordan Plieskatt, C. Richter King, Camila H. Coelho, Patrick E. Duffy, Carole Long, Takafumi Tsuboi, Kazutoyo Miura, Yimin Wu, Tomoko Ishino, Jonathan F. Lovell
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03688-z
Popis: Co-display of two P. falciparum malaria vaccine antigens (Pfs230D1+ and CSP) on the surface of immunogenic liposomes results in functional immune responses upon immunization of mice and rabbits. Combining both antigens produces immune responses that both block transmission and prevent infection.
Databáze: Directory of Open Access Journals
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