Investigation of Antitumor Substance from Trichoderma

Autor: V. M. Podboronov, A. E. Kuzovnikov, A. K. Zaitsev, I. P. Smirnova, T. T. Berezov
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Антибиотики и Химиотерапия, Vol 56, Iss 9-10, Pp 3-6 (2020)
Druh dokumentu: article
ISSN: 0235-2990
Popis: The effect of L-lysine-α-oxidase from Trichoderma harzianum Rifai on the functional activity of T-lymphocytes was investigated. It was shown that in a dose of 35 units/kg administered parentally the enzyme had no suppressive effect on the T-lymphocyte functional activity. An inhibitory effect of L-lysine-α-oxidase on some indices of the macrophages functional activity was observed. L-Lyzine-α-oxidase had a selective lymphotropic action and showed no mytostatic activity, which is in favour of the enzyme vs. other antitumor agents.
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