Autor: |
Mohammad Reza Hadjmohammadi, Azadeh Shariphi Aghili |
Jazyk: |
angličtina |
Rok vydání: |
2005 |
Předmět: |
|
Zdroj: |
Iranian Journal of Chemistry & Chemical Engineering, Vol 24, Iss 2, Pp 59-63 (2005) |
Druh dokumentu: |
article |
ISSN: |
1021-9986 |
Popis: |
Separation of ten sedative- hypnotic drugs was performed by RP-HPLC using mixed micellar mobile phase. Effect of temperature, type and amount of organic modifier in mobile phase on efficiency (N) and asymmetry factor (B/A) showed that, the appropriate conditions for a good separation were 35°C and 7% (V/V) butanol in mobile phase. Variations of selectivity factor versus butanol concentration, Mixture of SDS/ Brij- 35 concentrations and pH of mobile phase showed that the appropriate conditions were 7%(V/V), 15 mM SDS +1.0mM Brij-35 and pH=3 in mobile phase respectively. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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