Photodynamic action of the red laser on Propionibacterium acnes
| Autor: | Rogério Rodrigo Ramos, Jeferson Leandro de Paiva, José Paulo Franco dos Santos Gomes, Nagib Pezati Boer, José Maria Pereira de Godoy, Fernando Batigalia |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Anais Brasileiros de Dermatologia, Vol 92, Iss 5, Pp 622-625 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0365-0596 1806-4841 |
| DOI: | 10.1590/abd1806-4841.20175651 |
| Popis: | Abstract: Background: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. Objective: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. Method: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals. Results: It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study limitations: Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria. Conclusion: Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy. |
| Databáze: | Directory of Open Access Journals |
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