Clinical effectiveness of eprosartan and hydroxyzine in patients with mild to moderate arterial hypertension and coexisting anxiety
| Autor: | G. V. Pogosova, E. E. Koltunov, E. Yu. Spivak, Yu. S. Belova, A. V. Karpova |
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| Jazyk: | ruština |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 8, Iss 1, Pp 20-24 (2009) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| Popis: | Aim. То evaluate clinical effectiveness of eprosartan and hydroxyzine in patients with mild to moderate arterial hypertension (AH) and coexisting anxiety.Material and methods. The study included 34 patients (8 men, 26 women) aged 36—76 years (mean age 56,7+11,1 years) with Stage I-II AH. Stage I AH was registered in 6 participants, Stage II AH — in 28; mean AH duration was 9,29+6,2 years. All patients were randomised into two groups: main group (MG) and control group (CG). Fro 4 weeks, all participants received eprosartan (600 mg/day); MG individuals also received hydroxyzine (25—50 mg/day). The dynamics of clinico-psychological status and cognitive function in AH patients was assessed.Results. Hydroxyzine therapy was associated with improved psychological status: mean score for anxiety subscale reduced by 42'% (-5,2+0,47 points; p |
| Databáze: | Directory of Open Access Journals |
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