Does serum progesterone level impact the ongoing pregnancy rate in frozen embryo transfer under artificial preparation with vaginal progesterone? Study protocol for a randomized controlled trial

Autor:	Lin Haiyan, Yang Gang, Li Yu, Li Lin, Chen Xiaoli, Zhang Qingxue
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Vaginal progesterone HRT-FET Ongoing pregnancy rate Medicine (General) R5-920
Zdroj:	Trials, Vol 23, Iss 1, Pp 1-6 (2022)
Druh dokumentu:	article
ISSN:	1745-6215
DOI:	10.1186/s13063-021-05953-8
Popis:	Abstract Background In previous retrospective studies, low serum progesterone level on the embryo transfer day is associated with lower clinical pregnancy and ongoing pregnancy rates. Whether adding progesterone in low serum progesterone patients can rescue the outcome, there is no sufficient evidence from randomized controlled studies. Methods This trial is a clinical randomized controlled study (high serum progesterone vs low serum progesterone 1:1, 1:1 randomization ratio of intervention vs the control group with low serum progesterone). The eligible hormone replacement therapy—frozen embryo transfer (HRT-FET) cycles, will be recruited and randomly assigned to two parallel groups when serum progesterone is
Databáze:	Directory of Open Access Journals
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