Infiltration and Fat Droplet Phagocytosis by Macrophages in the Alveoli may be the Most Likely Characteristics of Fat Embolism

Autor: Bin Wang, Fu Zhang, Ning Xiao, Xiang Xu, Qi Wang, Xiao-Hui Tan, Tao Wang, Hui-Jun Wang, Dong-Ri Li
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Forensic Science and Medicine, Vol 2, Iss 3, Pp 171-174 (2016)
Druh dokumentu: article
ISSN: 2349-5014
DOI: 10.4103/2349-5014.191472
Popis: We report a case of nontraumatic fat embolism syndrome with large amounts of macrophages with phagocytized fat droplets in the alveoli. A 46-year-old male presented with a glass-cut injury in his little finger. The wound was debrided and sutured at the hospital, but he was found dead 43 h after treatment. Autopsy results showed that the patient had steatohepatitis, accompanied by histological findings of fat droplets in the pulmonary capillaries. In the alveoli, we found a large number of macrophages with phagocytized fat droplets that showed stained. To the best of our knowledge, this is the first report of such a case, and the paper proposes that fat droplets phagocytized by a large number of macrophages may be a characteristic feature of fat embolism, which may be relevant to forensic pathology practice.
Databáze: Directory of Open Access Journals