Intraoperative hypotension: Pathophysiology, clinical relevance, and therapeutic approaches

Autor: Karim Kouz, Phillip Hoppe, Luisa Briesenick, Bernd Saugel
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Indian Journal of Anaesthesia, Vol 64, Iss 2, Pp 90-96 (2020)
Druh dokumentu: article
ISSN: 0019-5049
0976-2817
DOI: 10.4103/ija.IJA_939_19
Popis: Intraoperative hypotension (IOH) i.e., low arterial blood pressure (AP) during surgery is common in patients having non-cardiac surgery under general anaesthesia. It has a multifactorial aetiology, and is associated with major postoperative complications including acute kidney injury, myocardial injury and death. Therefore, IOH may be a modifiable risk factor for postoperative complications. However, there is no uniform definition for IOH. IOH not only occurs during surgery but also after the induction of general anaesthesia before surgical incision. However, the optimal therapeutic approach to IOH remains elusive. There is evidence from one small randomised controlled trial that individualising AP targets may reduce the risk of postoperative organ dysfunction compared with standard care. More research is needed to define individual AP harm thresholds, to develop therapeutic strategies to treat and avoid IOH, and to integrate new technologies for continuous AP monitoring.
Databáze: Directory of Open Access Journals
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