Comparative liver function models for ruptured hepatocellular carcinoma: A 10-year single center experience

Autor: Jing-jing Wu, Zhan-guo Zhang, Peng Zhu, Abdoul-aziz Mba'nbo-koumpa, Bi-xiang Zhang, Xiao-ping Chen, Chang Shu, Wan-guang Zhang, Ren-jie Feng, Gan-xun Li
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Asian Journal of Surgery, Vol 42, Iss 9, Pp 874-882 (2019)
Druh dokumentu: article
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2018.12.015
Popis: Summary: Background/Objective: Previous studies have proposed several objective means for liver function assessment in hepatocellular carcinoma (HCC) patients; however, their efficiency in predicting survival of HCC rupture is unknown. Our study aims to confirm which is a better liver function model for ruptured HCC. Methods: A total of 230 patients with HCC ruptures at our center were included. Kaplan–Meier and Cox regression analyses were performed to compare long-term survival and short-term mortality. The 90-day mortality was compared with the area under the receiver characteristic curve. Logistic regression was used to determine the risk factors for 90-day deaths, and the discriminant ability of the model was measured. Results: There were significant differences in predicting OS of the Child-Pugh (CP) score in all patients, the non-surgical subgroup, and the surgical subgroup (all P
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