| Autor: |
Georgios Aidonidis, Ioannis Kanonidis, Vasileios Koutsimanis, Till Neumann, Raimund Erbel, Georgios Sakadamis |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Cardiology Research and Practice, Vol 2011 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
2090-0597 |
| DOI: |
10.4061/2011/342302 |
| Popis: |
Background. Levosimendan is an inotropic drug with unique pharmacological advantages in patients with acute heart failure. Scope of this study is to determine whether longer infusion patterns without the hypotension-inducing loading dose could justify an effective and safe alternative approach. Methods. 70 patients admitted to the emergencies with decompensated chronic heart failure received intravenously levosimendan without a loading dose up to 72 hours. Clinical parameters, BNP (Brain Natriuretic Peptide) and signal-averaged-ECG data (SAECG) were recorded up to 72 hours. Results. The 48-hour group demonstrated a statistically significant BNP decrease (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
