Emergence of New SARS-CoV2 Omicron Variants after the Change of Surveillance and Control Strategy

Autor: José María González Alba, Zulema Pérez-Martínez, José A. Boga, Susana Rojo-Alba, Juan Gómez de Oña, Marta E. Alvarez-Argüelles, Garbriel Martín Rodríguez, Isabel Costales Gonzalez, Ismael Huerta González, Eliecer Coto, Santiago Melón García
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Microorganisms, Vol 10, Iss 10, p 1954 (2022)
Druh dokumentu: article
ISSN: 2076-2607
DOI: 10.3390/microorganisms10101954
Popis: In January 2022, there was a global and rapid surge of the Omicron variant of SARS-CoV-2 related to more transmission. This coincided with an increase in the incidence in Asturias, a region where rapid diagnosis and containment measures had limited the circulation of variants. Methods: From January to June 2022, 34,591 variants were determined by the SNP method. From them, 445 were characterized by the WGS method and classified following pangolin program and phylogenic analysis. Results: The Omicron variant went from being detected in 2438 (78%) samples in the first week of January 2021 to 4074 (98%) in the third week, according to the SNP method. Using the WGS method, 159 BA.1 (35.7%), 256 BA.2 (57.6%), 1 BA.4 (0.2%) and 10 BA.5 (2.2%) Omicron variants were found. Phylogenetic analysis detected that three new sub-clades, BA.2,3.5, BA.2.56 and BF1, were circulating. Conclusions: The increase in the incidence of SARS-CoV2 caused the circulation of new emerging variants. Viral evolution calls for continuous genomic surveillance.
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