Gastroesophageal reflux disease in Sri Lanka: An island-wide epidemiological survey assessing the prevalence and associated factors.

Autor: Nilanka Wickramasinghe, Ahthavann Thuraisingham, Achini Jayalath, Dakshitha Wickramasinghe, Dharmabandhu N Samarasekera, Etsuro Yazaki, Niranga Manjuri Devanarayana
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: PLOS Global Public Health, Vol 4, Iss 5, p e0003162 (2024)
Druh dokumentu: article
ISSN: 2767-3375
DOI: 10.1371/journal.pgph.0003162
Popis: Gastroesophageal reflux disease (GERD) is commonly encountered in clinical practice in Sri Lanka. However, its prevalence in Sri Lanka is unknown. Our objective was to study the island-wide prevalence of GERD symptoms in Sri Lanka and its associated factors. A total of 1200 individuals aged 18-70 years (male: female 1: 1.16, mean age 42.7 years [SD 14.4 years]). were recruited from all 25 districts of the country, using stratified random sampling. An interviewer-administered, country-validated questionnaire was used to assess the GERD symptom prevalence and associated factors. Weight, height, waist, and hip circumference were measured. Heartburn and/or regurgitation at least once a week, an internationally used criterion for probable GERD was used to diagnose GERD. In this study, GERD symptom prevalence was 25.3% (male 42.1% and female 57.9%). Factors independently associated with GERD were inadequate sleep, snacking at midnight, sleeping within two hours of consuming a meal, skipping breakfast, increased mental stress, and certain medications used such as statins, and antihypertensive medications (p
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