Prognostic significance of the neutrophil-to-lymphocyte ratio in peripheral T-cell lymphoma: a meta-analysis

Autor:	Jia Liu, Shengnan Zhang, Ruihua Mi, Lin Chen, Qingsong Yin
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Neutrophil-to-lymphocyte ratio Peripheral T-cell lymphoma Prognostic model Meta-analysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Cytology QH573-671
Zdroj:	Cancer Cell International, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu:	article
ISSN:	1475-2867
DOI:	10.1186/s12935-021-02391-z
Popis:	Abstract The neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker may represent changes between inflammation and host immunity that affect the prognosis of peripheral T-cell lymphoma (PTCL). To comprehensively evaluate the NLR in PTCL, we performed a meta-analysis to investigate the relationship between the NLR and overall survival (OS) and progression-free survival (PFS). PubMed, Embase, Cochrane library, and China National Knowledge Infrastructure (CNKI) were searched for all relevant studies. Hazard ratios (HRs) and 95% confidence intervals (CIs) were obtained from each study. Heterogeneity among the included studies was checked to determine whether fixed or random effects model was used. In total, 8 studies with 921 patients were included for the meta-analysis. High NLR significantly correlated with worse OS (HR = 2.20, 95% CI 1.71–2.83, P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f878f26f4d254c5faa75d4ee0ba5533b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.