Dysbindin links presynaptic proteasome function to homeostatic recruitment of low release probability vesicles

Autor: Corinna Wentzel, Igor Delvendahl, Sebastian Sydlik, Oleg Georgiev, Martin Müller
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-02494-0
Popis: At the fly neuromuscular junction, postsynaptic receptor perturbation induces homeostatic enhancement of neurotransmitter release. Here, the authors show that the presynaptic proteasome controls a vesicle pool required for homeostatic plasticity and that dysbindin is required to access this pool.
Databáze: Directory of Open Access Journals