Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection

Autor: Husheem Michael, Francine C. Paim, Stephanie N. Langel, Ayako Miyazaki, David D. Fischer, Juliet Chepngeno, Joshua Amimo, Loic Deblais, Gireesh Rajashekara, Linda J. Saif, Anastasia N. Vlasova
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mSphere, Vol 6, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2379-5042
DOI: 10.1128/mSphere.00074-21
Popis: Rotavirus (RV) is a primary cause of malabsorptive diarrhea in children and is associated with significant morbidity and mortality, especially in developing countries. The use of antibiotics exacerbates intestinal microbial imbalance and results in the persistence of RV-induced diarrhea.
Databáze: Directory of Open Access Journals