Review of the role of cigarette smoking in diabetic foot

Autor: Nan Xia, Afsaneh Morteza, Fengyu Yang, Hong Cao, Aiping Wang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Diabetes Investigation, Vol 10, Iss 2, Pp 202-215 (2019)
Druh dokumentu: article
ISSN: 2040-1124
2040-1116
DOI: 10.1111/jdi.12952
Popis: Abstract Diabetic foot ulceration has been a serious issue over the past decades in Asia, causing economic and social problems. Therefore, it is important to identify and reduce the risk factors of diabetic foot. Cigarette smoking has been reported to be associated with diabetes and its macrovascular complications, but the relationship between smoking and diabetic foot ulcers is still unclear. In the present review, we summarize the effects of cigarette smoking on diabetic foot ulcers with respect to peripheral neuropathy, vascular alterations and wound healing. One underlying mechanism of these impacts might be the smoking‐induced oxidative stress inside the cells. At the end of this review, the current mainstream therapies for smoking cessation are also outlined. We believe that it is urgent for all diabetic patients to quit smoking so as to reduce their chances of developing foot ulcers and to improve the prognosis of diabetic foot ulcers.
Databáze: Directory of Open Access Journals
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