A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer

Autor: Michele Zeverino, Kristoffer Petersson, Archonteia Kyroudi, Wendy Jeanneret-Sozzi, Jean Bourhis, Francois Bochud, Raphael Moeckli
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Physics and Imaging in Radiation Oncology, Vol 7, Iss , Pp 32-38 (2018)
Druh dokumentu: article
ISSN: 2405-6316
DOI: 10.1016/j.phro.2018.08.002
Popis: Background and purpose: Adjuvant radiation therapy (RT) of the whole breast (WB) is still the standard treatment for early breast cancer. A variety of radiation techniques is currently available according to different delivery strategies. This study aims to provide a comparison of six treatment planning strategies commonly adopted for breast-conserving adjuvant RT and to use the Pareto concept in an attempt to assess the degree of plan optimization. Materials and methods: Two groups of six left- and five right-sided cases with different dose prescriptions were involved (22 patients in total). Field-in-Field (FiF), two and four Fields static-IMRT (sIMRT-2f and sIMRT-4f), Volumetric-Modulated-Arc-Therapy (VMAT), Helical Tomotherapy (HT) and Static-Angles Tomotherapy (TomoDirect™ – TD) were planned. Dose volume constraints were taken from the RTOG protocol 1005. Pareto fronts were built for a selected case to evaluate the reliability of the plan optimization process. Results: The best target dose coverage was observed for TD able to improve significantly (p
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