Mechanical Circulatory Support Systems in the Management of Ventricular Arrhythmias: A Contemporary Overview

Autor: Marco Valerio Mariani, Nicola Pierucci, Pietro Cipollone, Walter Vignaroli, Agostino Piro, Paolo Compagnucci, Andrea Matteucci, Cristina Chimenti, Claudio Pandozi, Antonio Dello Russo, Fabio Miraldi, Carmine Dario Vizza, Carlo Lavalle
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Clinical Medicine, Vol 13, Iss 6, p 1746 (2024)
Druh dokumentu: article
ISSN: 2077-0383
DOI: 10.3390/jcm13061746
Popis: Ventricular tachycardias (VTs) and electrical storms (ES) are life-threatening conditions mostly seen in the setting of structural heart disease (SHD). Traditional management strategies, predominantly centered around pharmacological interventions with antiarrhythmic drugs, have demonstrated limited efficacy in these cases, whereas catheter ablation is related with more favorable outcomes. However, patients with hemodynamically unstable, recurrent VT or ES may present cardiogenic shock (CS) that precludes the procedure, and catheter ablation in patients with SHD portends a multifactorial intrinsic risk of acute hemodynamic decompensation (AHD), that is associated with increased mortality. In this setting, the use of mechanical circulatory support (MCS) systems allow the maintenance of end-organ perfusion and cardiac output, improving coronary flow and myocardial mechanics, and minimizing the effect of cardiac stunning after multiple VT inductions or cardioversion. Although ablation success and VT recurrence are not influenced by hemodynamic support devices, MCS promotes diuresis and reduces the incidence of post-procedural kidney injury. In addition, MCS has a role in post-procedural mortality reduction at long-term follow-up. The current review aims to provide a deep overview of the rationale and modality of MCS in patients with refractory arrhythmias and/or undergoing VT catheter ablation, underlining the importance of patient selection and timing for MCS and summarizing reported clinical experiences in this field.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje