| Autor: |
Amal Abd El Hamid Mohamed, Nesma Ahmed Safwat |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Egyptian Journal of Medical Human Genetics, Vol 19, Iss 4, Pp 409-415 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1110-8630 |
| DOI: |
10.1016/j.ejmhg.2018.01.006 |
| Popis: |
Background: Percentage of smudge cells in CLL patients has recently been reported as a novel prognostic factor. Objectives: To investigate the impact of smudge cells percentage on the clinicolaboratory data of CLL patients and to evaluate the relationship between it and other prognostic factors in CLL. Methods: Ninety adults with CLL were enrolled. Smudge cells percentage was calculated by microscopic evaluation of blood smears. Testing of CD38 expression was done by immunophenotyping and detection of ATM, P53 deletions and trisomy 12 were performed using fluorescent in situ hybridization (FISH) Results: Lower smear cells percentage ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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