Impact of cardiovascular risk factors and cardiac diseases on mortality in patients with moderate to severe ARDS: A retrospective cohort study

Autor: Arnaud Gacouin, Pauline Guillot, Flora Delamaire, Alexia Le Corre, Quentin Quelven, Nicolas Terzi, Jean Marc Tadié, Adel Maamar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 22, Iss , Pp 200318- (2024)
Druh dokumentu: article
ISSN: 2772-4875
DOI: 10.1016/j.ijcrp.2024.200318
Popis: Background: History of coronary artery disease (CAD) and/or atrial fibrillation (AF) and/or valvular replacement (VR) are prevalent among patients admitted to intensive care units (ICUs). The impact of these conditions on outcomes in patients with acute respiratory distress syndrome (ARDS) remains insufficiently explored. Methods: We performed a retrospective study on prospectively collected data from patients with ARDS and a PaO2/FiO2 ratio ≤150 mmHg. Patients were admitted between January 2006 and March 2022. We used multivariable logistic regression analysis. The primary outcome was 1-year mortality from admission to the ICU; secondary outcomes included mortality at 28 days and 90 days. Results: Among 1.033 patients, 181 (17.5 %) had a history of CAD and/or AF and/or VR. History of CAD and/or AF and/or VR was independently associated with 1-year mortality (Odds-Ratio (OR) = 2.59, 95 % confidence interval (CI) 1.76–3.82, p
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